Glooko is not a sponsor and is not administering this clinical research study, nor are we implying that you will qualify. We are sharing this information with you so you can decide whether or not to seek more information or to participate. The information contained on this page is provided by vTv Therapeutics.
Sponsored by
vTv Therapeutics
CLINICAL RESEARCH STUDY
CATT1 Trial - Clinical Research Study
Evaluating an investigational medication called Cadisegliatin (TTP399) to reduce low blood sugar episodes and improve glucose management in adults with Type 1 Diabetes
New Study Aims to Reduce Lows
New Study Aims to Reduce Lows
Even with good insulin management, low blood sugar (hypoglycemia) episodes can still happen — and they can complicate your daily routine and long-term glucose goals.
The CATT1 clinical research study is evaluating whether a potential new oral treatment can help support more stable blood sugar in adults with type 1 diabetes.
vTv Therapeutics is studying an oral investigational medication designed to reduce low blood sugar episodes and improve A1C.
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Consent to Participate in Screening Survey
You are invited to take part in a clinical research study screening survey hosted by Glooko, Inc. on behalf of vTv Therapeutics LLC, the clinical research sponsor. This survey collects health and contact information to assess your eligibility to participate in a clinical research study. Your participation is voluntary and the survey should take about 5 minutes.
All responses collected by Glooko will be secured pursuant to our Privacy Notice. If you qualify for study participation, then your data will be shared with the clinical research sponsor and its approved third parties with your explicit consent.
Your decision to participate in the screening survey is voluntary and will not affect your medical care or benefits. By submitting your answers to the questions in the survey, you consent to participate in this screening survey, confirm you are at least 18 years old, and understand that no compensation or treatment will be provided for your participation in the screening survey. The screening survey is not, itself, a clinical research study, and you will not be automatically enrolled into a clinical research study without your explicit consent.
Do you consent to participate in this survey?
Clinical Research Study Details
CLINICAL RESEARCH STUDY DETAILS
vTv Therapeutics Inc. is conducting a clinical research study to evaluate an investigational medication that may help reduce the risk of low blood sugar (hypoglycemia) and improve A1C in adults with type 1 diabetes.
This study will assess how well TTP399, an investigational oral drug, works in lowering the chance of low glucose events while also supporting improved overall glucose control. The clinical research study will also evaluate the safety and tolerability of TTP399 in adults living with type 1 diabetes.
ELIGIBILITY CRITERIA
vTv Therapeutics is looking for individuals who:
Are 18 years of age or older
Have lived with T1D for at least five years
Have experienced at least 1 significant hypoglycemic event (< 54 mg/dL) in the last 2 months
The guidelines listed above are the primary eligibility criteria for this study. Only the clinical research study staff can determine if you meet all eligibility criteria for this study.
NOTE: This site is for US residents only
Why It's Important
What This Study Is Exploring — and Why It Matters
Fewer lows
Reducing low blood sugar episodes may help you feel better.
Better control
Improved A1C can support fewer glucose swings.
Everyday benefits
More stability may help make diabetes management feel easier.
The CATT1 clinical research study is evaluating an oral investigational treatment designed to help reduce low blood sugar events and improve A1C in adults with type 1 diabetes.
What's Involved
Here's what the study involves:
Study Duration
Approximately 9 months from start to finish
Study Visits
11 in-person visits and 11 convenient virtual visits
Study-Related Care
All study care provided at no cost to you
Compensation
Payment provided for your time and travel expenses
How It Works
How It Works
1
Answer a Short Survey
Complete a brief survey to see if you may qualify for the study. Takes just a few minutes.
2
Connect with Your Local Study Site
If eligible, you'll be contacted by qualified research staff in your area for more information.
3
Decide What's Right for You
Review the details and decide whether participation is a good fit for you.
Ready to Get Started?
Take the first step to see if you may qualify.
×
Consent to Participate in Screening Survey
You are invited to take part in a clinical research study screening survey hosted by Glooko, Inc. on behalf of vTv Therapeutics LLC, the clinical research sponsor. This survey collects health and contact information to assess your eligibility to participate in a clinical research study. Your participation is voluntary and the survey should take about 5 minutes.
All responses collected by Glooko will be secured pursuant to our Privacy Notice. If you qualify for study participation, then your data will be shared with the clinical research sponsor and its approved third parties with your explicit consent.
Your decision to participate in the screening survey is voluntary and will not affect your medical care or benefits. By submitting your answers to the questions in the survey, you consent to participate in this screening survey, confirm you are at least 18 years old, and understand that no compensation or treatment will be provided for your participation in the screening survey. The screening survey is not, itself, a clinical research study, and you will not be automatically enrolled into a clinical research study without your explicit consent.
Do you consent to participate in this survey?
Study Details & FAQs
More About the Clinical Research Study
Study Timeline Overview
Participation lasts about 9 months and includes several phases:
A screening period to confirm eligibility
A dose adjustment and training phase
A baseline assessment period
A 6-month treatment phase (where you may receive the study drug or placebo)
A short follow-up period to complete final assessments
Study Drug Information
How is the study drug taken? If eligible, you'll be randomly assigned to one of three groups. You may receive cadisegliatin at one of two dose levels, or a placebo (no active medication). The study drug is taken twice daily by mouth, with meals. All participants continue their regular insulin treatment.
Frequently Asked Questions
What is a clinical research study?
A clinical research study is a type of research that tests how well a new medical approach works in people.
What is informed consent?
Before joining the clinical research study, you'll review detailed information and can ask questions. Participation is always voluntary.
Will I know if I get the study drug?
No — this clinical research study is randomized and blinded, which means neither you nor the research team will know whether you're receiving the investigational drug or a placebo.
Questions & Share
Questions & Share
Need more information or want to help others learn about this opportunity?
Have Questions?
Glooko is here to help answer any questions about the clinical research study or eligibility requirements.
Help spread awareness about this clinical research study opportunity for the T1D community.
Every share helps connect more people with this opportunity
Disclaimer
This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Glooko does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content.