CATT1 Trial - Clinical Research Study
Glooko®
Important Notice:
Glooko is not a sponsor and is not administering this clinical research study, nor are we implying that you will qualify. We are sharing this information with you so you can decide whether or not to seek more information or to participate. The information contained on this page is provided by vTv Therapeutics.
CLINICAL RESEARCH STUDY

CATT1 Trial - Clinical Research Study

Evaluating an investigational medication called Cadisegliatin (TTP399) to reduce low blood sugar episodes and improve glucose management in adults with Type 1 Diabetes

New Study Aims to Reduce Lows

New Study Aims to Reduce Lows

Even with good insulin management, low blood sugar (hypoglycemia) episodes can still happen — and they can complicate your daily routine and long-term glucose goals.

The CATT1 clinical research study is evaluating whether a potential new oral treatment can help support more stable blood sugar in adults with type 1 diabetes.

vTv Therapeutics is studying an oral investigational medication designed to reduce low blood sugar episodes and improve A1C.

Man checking glucose levels in bedroom
Clinical Research Study Details

CLINICAL RESEARCH STUDY DETAILS

vTv Therapeutics Inc. is conducting a clinical research study to evaluate an investigational medication that may help reduce the risk of low blood sugar (hypoglycemia) and improve A1C in adults with type 1 diabetes.

This study will assess how well TTP399, an investigational oral drug, works in lowering the chance of low glucose events while also supporting improved overall glucose control. The clinical research study will also evaluate the safety and tolerability of TTP399 in adults living with type 1 diabetes.

ELIGIBILITY CRITERIA
vTv Therapeutics is looking for individuals who:
  • Are 18 years of age or older
  • Have lived with T1D for at least five years
  • Have experienced at least 1 significant hypoglycemic event (< 54 mg/dL) in the last 2 months
The guidelines listed above are the primary eligibility criteria for this study. Only the clinical research study staff can determine if you meet all eligibility criteria for this study.
NOTE: This site is for US residents only
Why It's Important

What This Study Is Exploring — and Why It Matters

Fewer lows

Reducing low blood sugar episodes may help you feel better.

Better control

Improved A1C can support fewer glucose swings.

Everyday benefits

More stability may help make diabetes management feel easier.

The CATT1 clinical research study is evaluating an oral investigational treatment designed to help reduce low blood sugar events and improve A1C in adults with type 1 diabetes.

What's Involved

Here's what the study involves:

Study Duration

Approximately 9 months from start to finish

Study Visits

11 in-person visits and 11 convenient virtual visits

Study-Related Care

All study care provided at no cost to you

Compensation

Payment provided for your time and travel expenses

How It Works

How It Works

1

Answer a Short Survey

Complete a brief survey to see if you may qualify for the study. Takes just a few minutes.

2

Connect with Your Local Study Site

If eligible, you'll be contacted by qualified research staff in your area for more information.

3

Decide What's Right for You

Review the details and decide whether participation is a good fit for you.

Ready to Get Started?

Take the first step to see if you may qualify.

Study Details & FAQs

More About the Clinical Research Study

Study Timeline Overview

Participation lasts about 9 months and includes several phases:

  • A screening period to confirm eligibility
  • A dose adjustment and training phase
  • A baseline assessment period
  • A 6-month treatment phase (where you may receive the study drug or placebo)
  • A short follow-up period to complete final assessments

Study Drug Information

How is the study drug taken? If eligible, you'll be randomly assigned to one of three groups. You may receive cadisegliatin at one of two dose levels, or a placebo (no active medication). The study drug is taken twice daily by mouth, with meals. All participants continue their regular insulin treatment.

Frequently Asked Questions

What is a clinical research study?

A clinical research study is a type of research that tests how well a new medical approach works in people.

What is informed consent?

Before joining the clinical research study, you'll review detailed information and can ask questions. Participation is always voluntary.

Will I know if I get the study drug?

No — this clinical research study is randomized and blinded, which means neither you nor the research team will know whether you're receiving the investigational drug or a placebo.

Questions & Share

Questions & Share

Need more information or want to help others learn about this opportunity?

Have Questions?

Glooko is here to help answer any questions about the clinical research study or eligibility requirements.

Contact Glooko at:

Disclaimer

This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Glooko does not take responsibility for possible health consequences of any person or persons reading or following the information in this educational content.

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